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Research

 
 
Sleep Research & Treatment Center
Publications
  1. Kales, A., Soldatos, C.R., Caldwell, A., Kales, J.D., Humphrey, F.J., Schweitzer, P., and Charney, D.:  Somnambulism:  Clinical characteristics and personality patterns.  Arch. Gen. Psychiatry 37:1406-1410, 1980.
  2. Kales, J.D., Kales, A., Soldatos, C.R., Caldwell, A., Charney, D., and Martin, E.D.:  Night terrors:  Clinical characteristics and personality patterns. Arch. Gen. Psychiatry 37:1413-1417, 1980.
  3. Soldatos, C.R., Vela-Bueno, A., Bixler, E.O., Schweitzer, P.K., and Kales, A.:  Sleepwalking and night terrors in adulthood:  Clinical EEG findings. Clin. Electroencephalogr. 11:136-139, 1980.
  4. Kales, A., Soldatos, C.R., Bixler, E.O., Ladda, R.L., Charney, D.S., Weber, G., and Schweitzer, P.K.:  Hereditary factors in sleepwalking and night terrors. Br. J. Psychiatry 137:111-118, 1980.
  5. Kales, A., Soldatos, C.R., Caldwell, A., Charney, D., Kales, J.D., Markel, D., and Cadieux, R.J.:  Nightmares:  Clinical characteristics and personality patterns. Am. J. Psychiatry 137:1197-1201, 1980.
  6. Kales, A., Bixler, E.O., Soldatos, C.R., Vela-Bueno, A.,  Caldwell, A.B., and Scarone, S.:  Biopsychobehavioral correlates of insomnia, I:  Role of sleep apnea and myoclonus nocturnus.  Psychosomatics 23:589-600, 1982.
  7. Kales, A, Caldwell, A.B., Soldatos, C.R., Bixler, E.O., and Kales, J.D.:  Biopsychobehavioral correlates of insomnia II:  MMPI pattern specificity and consistency.  Psychosom. Med. 45:341-356, 1983.
  8. Kales, A., Bixler, E.O., Vela-Bueno, A., Cadieux, R.J., Soldatos, C.R., and Kales, J.D.:  Biopsychobehavioral correlates of insomnia III:  Polygraphic findings of sleep difficulty and their relationship to psychopathology.  Int. J. Neuroscience 23:43-56, 1984.
  9. Tan, T.L., Kales, J.D., Kales, A., Soldatos, C.R., and Bixler, E.O.:  Biopsychobehavioral correlates of insomnia IV:  Diagnosis based on the DSM¿III.  Am. J. Psychiatry 141:357-362, 1984.
  10. Kales, J.D., Kales, A., Bixler, E.O., Soldatos, C.R., Cadieux, R.J., Kashurba, G.J., and Vela-Bueno, A.:  Biopsychobehavioral correlates of insomnia, V:  clinical characteristics and behavioral correlates.  Am. J. Psychiatry 141:1371-1376, 1984.
  11. Kales, A., Cadieux, R., Soldatos, C.R., Bixler, E.O., Schweitzer, P.K., Prey, W.T., and Vela-Bueno, A.:  Narcolepsy/cataplexy: I. Clinical and electrophysiologic characteristics.  Arch. Neurol. 39:164-168, 1982.
  12. Kales, A., Soldatos, C.R., Bixler, E.O., Caldwell, A., Cadieux, R., Verrechio, J., and Kales, J.D.:  Narcolepsy/cataplexy: II.  Psychosocial consequences and associated personality patterns.  Arch. Neurol. 39:169-171, 1982.
  13. Bixler, E.O., Kales, A., Vela-Bueno, A., Drozdiak, R.A., and Jacoby, J. A.:  Narcolepsy/cateplexy III:  Nocturnal sleep and wakefulness patterns.  Int. J. Neurosci. 29:305-316, 1986.
  14. Kales, A., Bixler, E.O., Soldatos, C.R., Cadieux, R.J., and Vela-Bueno, A.:  Narcolepsy/ cataplexy IV:  Diagnostic value of daytime nap recordings.  Acta Neurol. Scand. 75:223-230, 1987.
  15. Kales, A., Cadieux, R.J., Bixler, E.O., Soldatos, C.R., Vela-Bueno, A., Misoul, C.A., and Locke, T.W.:  Obstructive sleep apnea, I:  Onset, clinical course, and characteristics.  J. Chronic Dis. 38:419-425, 1985.
  16. Kales, A., Caldwell, A.B., Cadieux, R.J., Vela-Bueno, A., Ruch, L.G., and Mayes, S.:  Obstructive sleep apnea, II:  Associated psychopathology and psychosocial consequences.  J. Chronic Dis. 38:427-434, 1985.
  17. Kales, A., Bixler, E.O., Cadieux, R.J., Schneck, D.W., Shaw, L.C., III, Locke, T.W., Vela-Bueno, A., and Soldatos, C.R.:  Sleep apnea in a hypertensive population.  Lancet 2:1005-1008, 1984.
  18. Kales, A., Ansel, R.D., Markham, C.H., Scharf, M.B., and Tan, T.L.:  Sleep in patients with Parkinson's Disease and normal subjects prior to and following levodopa administration.  Clin. Pharmacol. Therap. 12:397-406, 1971.
  19. Kales, A., and Kales, J.:  Evaluation and Treatment of Insomnia. Oxford University Press, New York, 1984.
  20. Bixler, E.O., Vgontzas, A.N., Ten Have, T., Tyson, K., Kales, A.  Effects of Age on Sleep Apnea in Men: I. Prevalence and Severity.  Amer J Resp Crit Care Medicine 157:144-148, 1998.
  21. Bixler EO, Vgontzas AN, Ten Haven T, Lin H-M, Rein J, Vela-Bueno A, Kales A. Prevalence of sleep disordered breathing in women: effects of menopause. The American Journal of Respiratory and Critical Care Medicine, 163:608-613, 2001.
  22. Bixler, EO, Vgontzas AN, Ten Have T, Vela-Bueno A, Kales A: Association of hypertension and sleep disordered breathing, Archives of Internal Medicine, 160:2289-2295, 2000.
  23. Bixler EO, Vgontzas AN, Lin H-M, Vela-Bueno A, Kales A. Insomnia in Central Pennsylvania. Journal of Psychosomatic Research, 53:589-592, 2002.
  24. Bixler EO, Vgontzas AN, Lin H-M, Vela-Bueno A, Kales A. Women and sleep-related disorders. Eur Respir Mon, 25:204-218, 2003.
  25. Vgontzas AN, Papanicolaou DA, Bixler EO, Kales A, Tyson K. Chrousos GP: Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity.  Journal of Clinical Endocrinology and Metabolism, 1997; 82:1313-1316.
  26. Vgontzas AN, Bixler EO, Tan TL, Kantner D, Martin LF, Kales A: Obesity without sleep apnea is associated with daytime sleepiness.  Archives of Internal Medicine, 1998; 158:1333-1337.
  27. Vgontzas AN, Papanicolaou DA, Bixler EO, Lotsikas A, Zachman K, Kales A, Chrousos GP: Circadian interleukin-6 secretion and quantity and depth of sleep. Journal of Clinical Endocrinology and Metabolism, 1999; 84:2603-2607.            
  28. Vgontzas AN, Papanicolaou DA. Bixler EO, Hopper K, Lotsikas A, Kales A, Chrousos GP: Sleep apnea and daytime sleepiness and fatigue: relations with visceral obesity, insulin resistance and hypercytokinemia. Journal of Clinical Endocrinology & Metabolism, 2000; 85:1151-1158.
  29. Vgontzas AN, Bixler EO, Chrousos GP. Metabolic disturbances in obesity vs. sleep apnea: the importance of visceral obesity and insulin resistance. Journal of Internal Medicine, 2003;254:1-13.
  30. Loomis AL, Harvey EN, Hobart GA.  Cerebral state during sleep as studied by human brain potentials.  J Exp Psychol 21:127-144, 1937.
  31. Aserinsky E Kleitman N.  Regularly occurring periods of eye motility and concomitant phenomenon.  Science 118:273-274, 1953.
  32. Dement, W Kleitman N Cyclical variations in EEG during sleep and their relation to eye movements, body motility and dreaming. Clin Neurophysiol 9:673-690, 1957.
  33. Jacobson, A., Kales, A., Lehmann, D., and Hoedemaker, F.S.:  Muscle tonus in human subjects during sleep and dreaming.  Exp. Neurol. 10:418-424. 1964.
  34. Rechstshaffen, A., and Kales, A. (eds.):  A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects.  National Institutes of Health Publication No. 204, U.S. Government Printing Office, Washington, D.C., 1968.