Panic Disorder  - Respiratory abnormalities in nocturnal panic attacks.  A preliminary investigation.  In this study we are investigating the respiratory patterns, sensitivity to CO2, and sleep in panic disorder patients with and without nocturnal panic attacks and healthy volunteers.  This study is partly funded by Penn State Social Science Research Institute.

Treatment Resistant Depression - Randomized comparison of outcomes in patients with Treatment Resistant Depression (TRD) who receive VNS (Vagal Nerve Stimulation) therapy administered at different amounts of electrical charge.  This study will examine treatment outcomes for patients with TRD who are randomized to VNS Therapy administered at different amounts of electrical charge.  This study is a part of multi-center clinical trial sponsored by Cyberonics, Inc.